Antibacterial activity of 7,10-dihydroxy-8(E)-octadecenoic acid against food-borne pathogenic bacteria

 

Hye-Ran Sohn^a,Ka-Yeon Baek^a,Ching T. Hou^b,Hak-Ryul Kim^a,

                                                                                                     

Abstract

A bacterial strain Pseudomonas aeruginosa (PR3) has been intensively studied to produce a novel 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) from oleic acid or natural vegetable oils containing oleic acid. However, biological properties of DOD remained unknown so far. In this study, as a trial to determine the biological properties of DOD molecule, antibacterial activities of DOD against food-borne pathogenic bacteria were determined quantitatively and qualitatively. DOD presented strong antibacterial activities against all the bacterial strains tested with an MIC value being in the range of 125–500 μg/ml and there was no activity preference between gram-positive and gram-negative strains.

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Keywords

• Antibacterial activity;Bioconversion;7,10-dihydroxy-8(E)-octadecenoic acid;Oleic acid;Pseudomonas aeruginosa;Vegetable oil